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    Nutraceuticals
    Nutraceuticals

    Industry-leading nutraceutical processing & production

    From granulation to tableting, nutraceutical gummy production solutions and market leading capsule filling, Syntegon is your partner for complete supplement manufacturing.

    The global nutraceutical market is skyrocketing – with a projected growth of 6.5% CAGR or USD 618.09 billion, it is set to reach USD 1,089.43 billion in 2034 (data by Statista). Driven by this rapidly rising demand for dietary supplements and functional foods, manufacturers and contract manufacturing organizations (CMOs) are facing complex requirements: They need to deliver cleaner labels, tighter compliance, and ever-higher production volumes while also juggling natural powders that clog, blends that settle, and an increasing demand for plastic-free packaging solutions.

    Syntegon meets these challenges with a holistic line approach for nutraceutical processing: from high-shear granulation and fluid bed drying to precision supplement tableting and industry-leading capsule filling for dietary supplements. Film or sugar coating and process solutions for jellies and gummies round off the portfolio. One experienced partner, one validated line, maximum uptime.

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    Solving nutraceutical processing & production challenges

    Nutraceuticals based on natural ingredients are gaining traction – but processing them is challenging. From moisture-sensitive powders to clean-label requirements, and increasing regulatory demands, manufacturers and CMOs need flexible solutions for supplement manufacturing.

    Syntegon supports this with proven technology for supplement tablets, gummies, capsules, powders, and granules – enabling consistent quality, faster changeovers, and regulatory peace of mind.

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    Handling unstable natural nutraceutical powders

    Natural extracts, vitamins and organ powders often absorb moisture, vary in particle size, or expand during processing, which leads to clogs in granulation and nutraceutical capsule filling. Our Slide-gates, tamping pin compression, and fluid bed drying technologies ensure uniform and free-flowing batches for consistently high-quality supplement manufacturing.

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    Managing clean-label and personalization demands

    The shift towards clean-label supplements, vegan ingredients, and personalized doses requires frequent recipe changes and small batches – and therefore high flexibility in processing. Our modular systems enable rapid format changes, reliable handling of additive- free or probiotic powders, and scalability from R&D to high-speed filling of up to 450,000 nutraceutical capsules per hour.

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    Scaling production efficiently & compliantly

    Tight margins and volatile demand leave no room for downtime – and health‑claim regulations add complex validation processes. Manufacturers therefore need to scale their nutraceutical production efficiently without compromising compliance. Our cGMP, Part 11‑ready machine portfolio features quick‑change tooling and OEE analytics, reducing validation efforts, boosting uptime, and lowering total cost of ownership.

    Find your ideal nutraceutical processing solution

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    Granules

    Uniform, free‑flowing granules are the foundation of high‑quality tablets and nutraceutical capsules. Syntegon fluid bed dryers and high-shear mixers create perfectly agglomerated particles, and high downstream filling rates – even with natural powders.

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    Supplement capsules

    Whether filling powders, pellets, liquids, or even powder blends: Syntegon’s capsule fillers reach up to 450,000 capsules per hour. Our tamping pin technology enables precise weight accuracy and minimal product loss for every dietary supplement in gelatin or HPMC capsules.

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    Nutraceutical tablets

    From R&D to high-output machines, the Syntegon tablet presses process up to 400,000 tablets per hour while protecting fragile formulas. Our Nutra Services Team support you in the formulation and scale-up of organic, vegan, or effervescent tablets with spot‑on hardness and dissolution.

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    Functional gummies

    Highly precise process lines turn vitamins and minerals into the tasty gummies both children and adults love. Smart solutions for cooking, depositing (starchless or starchbased), rapid cooling, and product finishing ensure consistent shape, weight, and texture as well as a high-quality finish.

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    Still looking for the right fit? Get tailored guidance from our experts or download our knowledge reports for deeper insights into nutraceutical production.

    Contact our team

    Key benefits of Syntegon’s nutraceutical manufacturing lines

    Flexibility across all products
    Combination filling and tamping‑pin technology process powders, pellets, or liquids, letting you shift from granules to capsules or tablets without new equipment. Our nutraceutical candy equipment enables a variety of colors, flavors, and recipes for your functional sweets, so you can always meet market demand.
    Maximum uptime, minimal product loss
    Quick‑change tooling, operator-friendly and thorough CIP (cleaning in place) solutions as well as OEE analytics reduce waste and downtime – for stable output and faster return on investment.
    Lowest total cost of ownership
    End‑to‑end Syntegon solutions simplify project and vendor management and deliver reliable long-term performance that protects your margins.

    From processing raw ingredients to manufacturing and finishing your final product, syntegon.livebines all steps in one line. This means consistent quality and fast implementation – on supplement tablet and capsule lines as well as on lines for functional sweets.

    What this means for you:

    • Fast and simple project management with one vendor and one service team
    • Easy implementation of additional upstream or downstream equipment
    • Comprehensive support for optimizing and testing formulations and processes
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    Real-world wins with nutraceutical production solutions from Syntegon

    From tricky powders to liquid-filled capsules, these use cases show how nutraceutical manufacturers have solved real production challenges and scaled fast with Syntegon technology.

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    Precise liquid capsule dosing

    Together with BASF, Syntegon ran melted excipient matrices on a GKF 1400 L and achieved <0 .2% weight RSD with servo-controlled liquid dosing at 66,000 capsules per hour – enabling a smooth scale-up path for low-solubility APIs.

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    Lubricant switch success

    Replacing magnesium stearate with Compritol® on a TPR 200 preserved tablet hardness and avoided disintegration delays, while maintaining low ejection forces.

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    Waxy powder breakthrough

    A waxy myristic-acid blend clogged conventional fillers. Syntegon retrofitted a GKF 2600 with single tamping, Slide-gate, and special pins, thereby boosting the output from 40,000 to 156,000 capsules per hour – and pushing yields past 97%.

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    Trusted by nutraceutical producers worldwide

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    Natural powders mastered, OEE soars

    “Syntegon’s capsule fillers have elevated our production to new levels of precision and efficiency. Natural supplements now exceed quality expectations, downtime is significantly reduced, and we’re now capable of running beadlets with Syntegon’s Slide-gate technology.”

    Joaquin Báez, Director of Operations, Florida Supplement

    FAQs about nutraceutical processing equipment

    Below you’ll find quick answers to the most common questions about Syntegon’s solutions for supplement manufacturing. In case you did not find what you were looking for, ask our experts and they will help you find the right solution.

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    Absolutely. We combine several features to ensure reliable powder handling:

    • Slide-gate feeders minimize start-up losses and bridging
    • Tamping pin dosing compacts fluffy blends for weight accuracy
    • Optional fluid-bed pre-drying reduces stickiness before filling

    Toolless changeovers between capsule sizes take less than 30 minutes. Tablet formats can be swapped in under 20 minutes – keeping OEE high, even with small batches.

    Yes, every Syntegon nutraceutical line is delivered with:

    • cGMP-compliant surfaces and hygienic design
    • Part 11-ready HMIs with electronic batch records, e-signatures, and audit trail
    • Validation documents (DQ/IQ/OQ) for faster regulatory approval

    Definitely. Our modular GKF capsule fillers and TPR tablet presses share controls and recipe management that enable you to:

    • Begin with an R&D or pilot model
    • Scale up to outputs > 450,000 units per hour on the same HMI
    • Re-use validation data for faster validation, saving time and cost

    We offer comprehensive, global services including:

    • 24/7 remote troubleshooting and VPN diagnostics
    • Global field-service teams for on-site intervention
    • Predictive maintenance packages and local spare parts hubs
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    We help you lower your TCO by combining durable components with advanced designs and energy-efficient technology that enables:

    • Up to 50% less material waste thanks to Slide-gate dosing
    • Extended maintenance intervals to reduce downtime
    • Faster ROI through higher uptime and lower utility consumption

    Looking for more ways to optimize your nutraceutical production and processing? Explore our comprehensive service portfolio to see how Syntegon’s expertise can support your success.

    Whether you need tailored Service Agreements, Expert Services, or ongoing support, we help you unlock long-term production success. Discover how we can work together to achieve your goals.

    Service Agreements
    Service Agreements

    Find out more about our Service Agreements here.

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    Digital Solutions
    Digital Solutions

    Find out more about Digital Solutions here.

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    Maintenance
    Maintenance

    Find out more about Maintenance here.

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    Technical Support
    Technical Support

    Find out more about Technical Support here.

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    Modernizations
    Modernizations

    Find out more about Modernizations here.

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    Training
    Training

    Find out more about our Training here.

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    Expert Services
    Expert Services

    Find out more about our Expert Services here.

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    Downloads

    Tablet Press Brochure
    Tablet Press Brochure

    Ideal for the tablet compression of pharmaceutical and nutraceutical products – from R&D and pilot use to high volumes.

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    GKF Capsylon Series Flyer
    GKF Capsylon Series Flyer

    The capsule filling machine is specially designed for the health and nutraceutical industry

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    GKB 2100 Flyer
    GKB 2100 Flyer

    The GKB 2100 hard capsule sealing machine is suitable for both hard gelatin and HPMC (plant-based) capsules

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    Knowledge Report Waxy and Sticky Powder
    Knowledge Report Waxy and Sticky Powder

    Explore pharma solutions for handling waxy powders, reducing machine blockages, and optimizing dosing, tailored to industry needs.

    Download
    Lubricant comparison study on tablet presses
    Lubricant comparison study on tablet presses

    Optimize tablet production using alternative lubricants to overcome magnesium stearate challenges in pharma manufacturing

    Download
    Knowledge Report Bioavailibility of low soluble API - formulation solutions in capsules
    Knowledge Report Bioavailibility of low soluble API - formulation solutions in capsules

    Explore formulations, viscosity handling, GKF liquid-dosing tech for uniform low-soluble APIs; quick scale-up and improved content uniformity.

    Download
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    Interested in processing and packaging solutions for nutraceutical products?

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