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    Pen & Auto-Injector assembly machines for modular flexibility

    Handle new device formats with modular Pen and Auto-Injector assembly machines designed for smooth scale-up.

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    Flexible and modular Pen and Auto-Injector assembly systems

    Faster drug development and shorter launch timelines, fueled by “off-the-shelf” injection devices, also increases the pressure on final assembly systems.

    As your strategic lifecycle partner, the Syntegon assembly systems portfolio matches the drug development process needs.

    Meet demand, streamline development and ramp up faster

    How to scale production when demands are going up?

    Scalable processes across platforms.

    How to prepare for the unknown future device requirements?

    Add new devices or features later with minimal rework.

    How to assemble different types of devices?

    Fast and intuitive format changeovers

    Auto-Injector assembly machine from clinical batches to scale-up

    MedTech assembly platform

    Clinical and small batch assembly

    Produce compliant clinical and small batches with a standard assembly setup. 

    Shared process basis for technology transfer

    A shared platform and common recipe model reduces friction, rework, and revalidation during tech transfer.

    Compatible with multiple devices

    Assemble different Pens or Auto-Injectors, or even both, on the same machine.
     

    Customizable level of automation for commercial production

    Configure automation from semi-auto to fully automated lines to match volume and budget needs.

    Tray Handling units

    Automated tray handling increases throughput and reduces manual handling steps.

    Inline labeling

    Reduce handling steps and automate the labelling process of your device inline with the same speed as assembly.

    Identical HMI and user interface across platforms

    The same intuitive HMI across platforms cuts training time and reduces operator errors.

    MedTech assembly platform

    Clinical and small batch assembly

    Produce compliant clinical and small batches with a standard assembly setup. 

    MedTech assembly platform

    Shared process basis for technology transfer

    A shared platform and common recipe model reduces friction, rework, and revalidation during tech transfer.

    MedTech assembly platform

    Compatible with multiple devices

    Assemble different Pens or Auto-Injectors, or even both, on the same machine.
     

    MedTech assembly platform

    Customizable level of automation for commercial production

    Configure automation from semi-auto to fully automated lines to match volume and budget needs.

    MedTech assembly platform

    Tray Handling units

    Automated tray handling increases throughput and reduces manual handling steps.

    MedTech assembly platform

    Inline labeling

    Reduce handling steps and automate the labelling process of your device inline with the same speed as assembly.

    MedTech assembly platform

    Identical HMI and user interface across platforms

    The same intuitive HMI across platforms cuts training time and reduces operator errors.

    Clinical and small batch assembly

    Clinical and small batch assembly
    Shared process basis for technology transfer
    Compatible with multiple devices
    Customizable level of automation for commercial production
    Tray Handling units
    Inline labeling
    Identical HMI and user interface across platforms

    Compare Auto-Injector & Pen assembly machine options

    Overall 4 Solutions
    Output performance
    Format range
    Special features
    In- and outfeed of components
    Line integration
    Benefits
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    RMA
    Output performance
    Semi-automated small-scale production for clinical and small batches
    Format range
    Standard 4-component Pens and 3-component Auto-Injectors as well as bespoke devices on request
    Special features
    Operator friendly and Award winning UX design, off-the-shelf for standard formats, standard options like container inspection
    In- and outfeed of components
    Manual
    Line integration
    Stand-alone system
    Benefits

    Best if you want:

    • Semi-automated small-scale production for clinical and commercial batches 
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    MRA-S
    Output performance
    Commercial-scale final assembly at 50 ppm
    Format range
    Standard 4-component Pens and 3-component Auto-Injectors as well as bespoke devices on request
    Special features
    Semi-automated small-scale production for clinical and commercial batches
    In- and outfeed of components
    Semi- or full-automatic depending on needs
    Line integration
    Semi-automated production with connection to both up- and downstream equipment.
    Benefits

    Best if you want:

    • Reliable commercial output up to 50 ppm at a very low footprint
    • Multiple devices on the same machine
    • Inline labeling
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    MRA-A
    Output performance
    Commercial-scale final assembly at 100 ppm
    Format range
    Standard 4-component Pens and 3-component Auto-Injectors as well as bespoke devices on request
    Special features
    Quick and easy format change, inline labeling
    In- and outfeed of components
    Fully automated with tray handling and feeding systems
    Line integration
    Fully automated production with connection to both up- and downstream equipment
    Benefits

    Best if you want:

    • Reliable commercial output up to 100 ppm at a very low footprint
    • Multiple devices on the same machine
    • Inline labeling 

     

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    MXA
    Output performance
    Fully automated high-volume commercial production up to 200 ppm
    Format range
    Standard 4-component Pens and 3-component Auto-Injectors as well as bespoke devices on request
    Special features
    Flexible platform built on a magnetic track transport system
    In- and outfeed of components
    100% automated with tray handling, bulk feeding systems and potentially pallet handling
    Line integration
    Fully automated production with connection to both up- and downstream equipment
    Benefits

    Best if you want:

    • Fully automated high-volume production for a single or a few different devices
       
    Featured_Download_Teaser_MedTech

    Download the Syntegon MedTech assembly portfolio overview

    Download to get an overview and compare the different Pen and Auto-Injector platforms from R&D to commercial production.

    • Find the right solution for your current needs
    • Plan the lifecycle of your product and therefore manufacturing capabilities
    • Get inspired and learn from the experts
    Download

    Auto-Injector & Pen assembly machine solutions for efficient, flexible scale-up

    1080x1080_KistlerHMI

    Same press kit basis from R&D to high-volume production

    Scale on a common process basis.
    quick format change

    Quick format change for Pens and Auto-Injectors

    Adapt device formats without slowing assembly.
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    Inline or stand-alone labeling for Pens and Auto-Injectors

    Add labeling where it fits your assembly setup.
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    Case Study

    PCI Pharma Services cuts changeover time in Auto-Injector assembly

    PCI needed a flexible Auto-Injector assembly setup for diverse customer formats. Syntegon delivered a semi-automated modular machine with labeling and tray loading, enabling tool-free changeovers in less than 2 hours and coverage for 80% of today’s Auto-Injector market. 

    value-icon-innovative-technologies
    Innovative Technologies We enable market leadership.
    Read the full story
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    Highlight Topic

    Read our ONdrugDelivery article on scalable assembly

    See how small-batch injectable production can scale toward commercial output. Our ONdrugDelivery article explores modular assembly equipment for injection devices and the role it plays in efficient ramp-up.

    Read the ONdrugDelivery article

    Your strategic lifecycle partner for Pen & Auto-Injector assembly

    service-life-cycle
    Ready for everything from start to routine

    From installation to optimization Syntegon supports you with structured service packages, training and specialists for safe, stable and resilient production across the lifecycle. 

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    service-life-uptime
    Secure availability – every day

    Fast spare parts, qualified support, and preventive maintenance help you avoid unplanned downtime, protect performance, and keep daily operations reliable.

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    service-future-ready
    Make your line fit for tomorrow

    Scalable retrofits and data solutions help you adapt to new demands, improve OEE, and keep your lines future-proof across changing requirements.

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    Pen & Auto-Injector assembly knowledge hub

    Auto-Injector assembly overview
    Auto-Injector assembly overview

    See how shared press kit hardware and controls support seamless scale-up.

    Download
    MedTech assembly overview
    MedTech assembly overview

    Compare R&D, clinical and commercial assembly platforms for Pens and Auto-Injectors.

    Download
    MRA Auto-Injector flyer
    MRA Auto-Injector flyer

    Review quick format change, inline labeling and modular expansion for MRA assembly.

    Download
    MRA commercial flyer
    MRA commercial flyer

    Compare 50 ppm and 100 ppm MRA configurations for commercial device assembly.

    Download
    RMA assembly flyer
    RMA assembly flyer

    See how RMA handles clinical trials and small batches with a clear path to higher output.

    Download
    Small-batch manufacturing guide
    Small-batch manufacturing guide

    Learn how modular small-batch systems scale without extensive revalidation processes.

    Download
    RDA assembly success story for flexible Auto-Injector formats
    RDA assembly success story for flexible Auto-Injector formats

    See how PCI Pharma Services assembles multiple Auto-Injector formats with the RDA. Learn how modular design and fast changeovers reduce downtime and expand format coverage.

    Download

    Frequently asked questions

    Modular assembly systems support scale-up by keeping the core process basis consistent across production stages. Syntegon’s RANGE platform uses the same press kit hardware and controls across semi-automated and fully automated equipment. Standardized assembly processes and harmonized HMIs keep workflows aligned from clinical trials and small batches to high-volume production. The documented platform range covers output from 2 to 200 devices per minute. 

    Syntegon’s documented platforms are built for Pens and Auto-Injectors. Standard configurations include 4-piece pens and 3-piece auto-injectors, each including the primary container. The platforms are also designed for quick format change and modular expansion, which gives manufacturers room to adapt assembly for future device requirements within the documented platform concept. 

    RMA is the semi-automated platform for clinical trials and small batches. On this page, MRA-S refers to a 50 ppm commercial MRA configuration with semi-automatic infeed and outfeed. MRA-A refers to a 100 ppm commercial MRA configuration with automatic tray infeed and outfeed. MXA is the fully automated platform for high-volume commercial production. Together, these options create a clear path from early-stage assembly to larger-scale output. 

    Yes. Syntegon documents inline and stand-alone labeling as optional equipment for MRA-based Pen and Auto-Injector assembly. Available options also include inline labeling with vision, device marking by laser or InkJet, and outfeed to downstream packaging equipment. That lets manufacturers add labeling within the broader assembly concept instead of treating it as a separate stand-alone step. 

    Yes. Syntegon documents modular expansion across the platform family. MRA systems can be upgraded with more autonomous infeed and outfeed solutions, and additional modules can be fitted within the assembly cell. RMA also includes quick format couplings for future device expansions. At platform level, the shared press kit hardware and controls support a clear path from clinical trials and small batches to higher-output production. 

    Interested in Pen and Auto-Injector solutions?

    Interested in Pen and Auto-Injector solutions?

    Talk to a Syntegon expert to learn more about Pen and Auto-Injector solutions.

    Learn more

    News

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    Discover how Syntegon enhances pharmaceutical education with Dr. Marcus Knöll's insights at the University of Maryland's Tablets and Capsules Short Course.

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